Recent studies have shown the use of naltrexone for detox to be effective in fostering sobriety in heroin, and amphetamine dependent patients in a 9-week randomized, double-blind trial. Naltrexone implants placed in drug rehab clients resulted in higher retention rates. 48% of patients with naltrexone implants showed decreased heroin and amphetamine use and improved clinical conditions for the patients.
Treatment with COMT inhibitors may improve adherence to suboxone maintenance treatment for opioid addiction. In a study of 55 opiate detox patients who had failed to comply with initial drug rehab goals, 18% remained abstinent for longer than 6 months when they received the COMT inhibitor entacapone in addition to subutex. Another 61 patients were able to achieve abstinence using long-acting naltrexone. This is the first study of its kind to demonstrate COMT-inhibitors’ anticraving effects.
Drug rehab studies have shown stress has been associated with impaired decision making and high risk for relapse, even after long periods of abstinence. In a recent controlled, randomized protocol, the positive effects of stress on performance were prevented by the antagonist propranolol as early as after 20 days and as late as 14 months after abstinence began, suggesting a potential positive role for beta-blockers in decreasing the risk for relapse.
Because decision-making deficits are common in patients who need drug rehab programs, individuals with more prominent deficits may particularly benefit from treatment in a residential setting.
Naltrexone For Detox
613 Northlake Blvd
North Palm Beach, FL 33408
Fax (561) 557-3880